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Inhalt
Principle Investigator
Dr. sc. hum. Nanni Schmitt
Head of Research Laboratory
Phone 0621/383-71304
Telefax 0621/383-71329
nanni.schmitt@medma.uni-heidelberg.de
Preclinical 3D models of MDS and AML
Dr. sc. hum. Eva Altrock
Contact
Phone +49 621/383-71314
eva.altrock@medma.uni-heidelberg.de
Fields of expertise
- Improvement of MDS modelling
- 3D Ossicle model as an alternative method
- 3D in vitro cell culture of MDS MSCs and HSPCs
- (PhD students: : cand. med. Ann-Christin Belzer, cand. med. Julia Fahle, cand. med. Jan Sütterlin)
Preclinical testing of novel therapeutic substances
Dr. sc. hum. Nanni Schmitt
M. sc. Lisa Burger
Contact
Phone +49 621/383-71304
nanni.schmitt@medma.uni-heidelberg.de
Fields of expertise
- Generation of MDS models to be used as pre-clinical platforms, and their further optimization
- Pre-clinical assessment of NK cell based therapies for treatment of AML and high-risk MDS
- PhD students: cand. med. Alexandra Beck, Teresa Klink und Meret Hahn
Contact
Phone +49 621/383-71310
lisa.burger@medma.uni-heidelberg.de
Fields of expertise
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Preclinical test systems to charactarize myeloid neoplasia
Investigations of the pathomechanism of myeloid neoplasms
Dr. sc. hum. Vladimir Riabov
M. sc. Alessa Klär
M.Sc.Ling Ma
Alumni
Dr. med. Qingyu Xu
Contact
Phone +49 621/383-71310
Fields of expertise
- Role of MSC/HSC crosstalk in the pathogenesis of myeloid neoplasms (MDS and MPN), molecular studies (Vladimir Riabov and Alessa Klär)
- R-loops mediated replication stress as a novel therapeutic target in MDS with splicing factor mutations (Vladimir Riabov and MD student: Marie Demmerle)
- Investigation of the role of BM microenvironment in MDS (Vladimir Riabov and Alessa Klär)
Contact
Phone +49 621/383-71303
Fields of expertise
- Role of MSC/HSC crosstalk in the pathogenesis of myeloid neoplasms (MDS and MPN), molecular studies (Vladimir Riabov and Alessa Klär)
- Investigation of the role of BM microenvironment in MDS (Vladimir Riabov and Alessa Klär)
Contact
Phone 0621- 383- 71310
ling.ma@medma.uni-heidelberg.de
Fields of expertise
- Role of Erythroferrone (ERFE) in the patho-mechanism of MDS (with V. Riabov)
- analyzing the biological ERFE effects on the bone marrow microenvironment (BMME) (with V. Riabov)
Molecular analysis of myeloid neoplasms
Dr. med. Alexander Streuer
Contact
Phone +49 621/383-71314 or -4115
Fields of expertise
- Next Generation Sequencing (RNA sequencing, whole exome sequencing, single-cell RNA sequencing)
- Pipelines for the analysis of clonal alterations of leukemic cells
- “Radiomics”- the role of spatial sampling for Contact: therapy decisions and outcome
Scientific Management/ Study Coordination
Dr. rer. med. Felicitas Rapp
Contact
Phone +49 621/383-71314
Fields of expertise
- Management of research projects
- Administration of funding
- Preparation of new clinical studies
- Coordination of ongoing studies
Technicians
Verena Nowak
Faculty board member
Iris Palme
Julia Obländer
Fields of expertise
- Research projects
- Clinical Routine: Cell culture, FACS, PCR
- Biosampling
Elena Speck B.Sc.
Nadine Weimer
(parental leave)
Nadine Vo
Contact
Phone + 49 621/383-71313
Fax +49 621/383-71329
Clinical studies
- Innovative novel therapies
- Clinical studies for patients with myelodysplastic neoplasia or leukemia
- Close interaction with scientists: “from bench to bedside”
- Contact: Prof. Wolf-Karsten Hofmann
